Beautiful city of Rothenburg ob der Tauber-Germany!
Saturday, February 29, 2020
Sunday, February 23, 2020
Best Supplements for the Brain: Four Supplements proven to protect your Brain!
By Erik Bredemeyer
Best Supplements for the Brain: Four Supplements proven to protect your Brain!
BEST supplements for Brain Health:
The importance of Keeping your mind sharp throughout your life is self-evident, but as we age preserving brain health becomes paramount. Increasing evidence is shedding light on the supplements that can help boost the brain and its cognitive functions.
Here are four such supplements!
The brain is arguably the most important organ in the body, helping you to control and coordinate actions and reactions, think and feel, and process memories and experience feelings.
In other words, the brain forms the bedrock of what it means to be human. The ageing process can pose a threat to this essential organ, causing mild cognitive impairment (MCI), the stage of cognitive decline that precedes dementia.
It can involve problems with memory, language, thinking and judgment that are greater than normal age-related changes.
While it is not exactly known how to prevent cognitive decline, promising evidence suggests lifestyle interventions can preserve and boost breath health, offering protection against brain decline.
While it is not exactly known how to prevent cognitive decline, promising evidence suggests lifestyle interventions can preserve and boost breath health, offering protection against brain decline.
According to UK-based nutritionist Libby Limon, dietary supplements hold particular promise in this area.
Here are five supplements shown to stave off the risk of cognitive decline:
Here are five supplements shown to stave off the risk of cognitive decline:
B Vitamins:
According to Limon, B vitamins, particularly folate are proving to play a major role in brain development and health from foetus all the way to old age.
Folate is one of the B-vitamins is needed to make red and white blood cells in the bone marrow, convert carbohydrates into energy, and produce DNA and RNA.
How does it boost breath health?
Limon explains: “Folate is integral in the methylation pathway which in the brain supports DNA replication.
“How efficient our methylation pathway is down to genetics, but supporting that pathway with plenty of dietary folate can make all the difference, especially to those that are poor methylators.”
“How efficient our methylation pathway is down to genetics, but supporting that pathway with plenty of dietary folate can make all the difference, especially to those that are poor methylators.”
DNA methylation is an example of one of the many mechanisms of epigenetics. Epigenetics refers to inheritable changes in your DNA that don’t change the actual DNA sequence. Early findings suggest DNA methylation may reduce the genetic risk of developing certain conditions.
Turmeric:
According to Limon, inflammation is often considered the root cause of degenerative brain diseases.
“Turmeric is potent anti-inflammatory, as such it has already shown potential in animal studies to reduce or help prevent brain cell damage,” she says. As research progresses to human studies, turmeric’s potential in boosting brain health is beginning to be unleashed.
“Turmeric is potent anti-inflammatory, as such it has already shown potential in animal studies to reduce or help prevent brain cell damage,” she says. As research progresses to human studies, turmeric’s potential in boosting brain health is beginning to be unleashed.
Bacopa Monnieri:
Bacopa Monnieri is an Ayurvedic herb that has been traditionally used to sharpen the mind and the intellect. As Limon reports, modern studies show like turmeric has anti-inflammatory effect on brain cells, thus have a protective effect. “Healthy cells mean a healthy and sharp mind,” she adds.
Lion’s Mane Mushrooms:
“Research has found that lion’s mane mushrooms may protect against dementia, reduce mild symptoms of anxiety and depression and help repair nerve damage,” explains Limon. In one study, lion’s mane dietary supplements appeared to give mice better object recognition and recognition memory.
Other researchers have concluded that the mushrooms may have the potential to treat or prevent diseases that cause a decline in cognitive health, such as Parkinson’s disease and Alzheimer’s disease. Alzheimer’s disease is the leading cause of dementia in the USA.
Saturday, February 22, 2020
Friday, February 21, 2020
Human trials take inflating needle-filled smart pills closer to market!
By Erik Bredemeyer
Human trials take inflating needle-filled smart pills closer to market!
Who wouldn’t want to be able to replace regular painful injections with a smart pill? That’s what San Jose, California-based company Rani Therapeutics has developed with its innovative RaniPill.
While the RaniPill looks like a regular capsule, when its outer layer dissolves in the intestine, a miniature balloon inflates inside and pushes a tiny needle into the intestinal muscular wall to inject its contents.
Because the intestine has no pain receptors, all of this happens without the patient feeling a thing. The balloon then deflates, and the pill can be passed via the, err, normal channels.
On the surface, this high-tech pill of the future sounds like the kind of Rube Goldberg solution that will never make it past initial prototypes. You’d be wrong, however, since the RaniPill just underwent a human trial, taking it one step closer to market.
In the trial, participants were given RaniPills containing octreotide, a drug prescribed as part of the treatment for certain types of tumors found in the intestines and pancreas.
“The phase one clinical study of Octreotide-RP was conducted in Australia with 58 healthy adult volunteers,” Mir Imran, CEO and founder of Rani Therapeutics, told Digital Trends. “The test group was comprised of both male and female subjects aged 18 to 55.
Of the 58 participants, 52 were dosed with Octreotide-RP, the RaniPill loaded with octreotide. A control group of six participants was given an intravenous injection of an identical dose of octreotide.”
The study confirmed the RaniPill was well tolerated, meaning the subjects could easily swallow it and did not feel any pain or other unpleasant sensations. It also demonstrated that the RaniPill can safely and effectively deliver drugs into the intestinal wall in the appropriate dosage.
The company is planning further tests later in the year, and is in discussions with pharmaceutical companies and regulators in the United States and Europe. Initially, the company hopes to use the RaniPill to deliver nine drugs, including octreotide and insulin.
“[When it will make it to market depends] on the timing of FDA approval,” Imran continued. “We are engaged in discussions with the FDA, and expect approval in two to three years.”
“[When it will make it to market depends] on the timing of FDA approval,” Imran continued. “We are engaged in discussions with the FDA, and expect approval in two to three years.”
Wednesday, February 19, 2020
Transhumanists Believe Technology Can End Human Suffering!
Transhumanists Believe Technology Can End Human Suffering!
According to one of the world’s current most prominent transhumanists, new and future technology can one day be used to free humans and animals from suffering by eliminating all of pain, making everything much simpler.
Transhumanism:
Stemming from the idea of self-improvement, transhumanism is an international philosophical movement that advocates for the human condition’s transformation by enhancing both human physiology and intellect via the use of available sophisticated technologies.
The World Transhumanist Association, since renamed Humanity+, is the main international body that promotes transhumanist ideas all over the world. And now, one of its founders argued that in order to do this, humans and humans must first “end suffering,” which can be achieved by making use of technology to artificially enhance human capabilities and limitations.
“The strand of transhumanism I am most interested in is this idea we can use biotechnology to phase out suffering via genetic engineering, not just in humans but also in non-human animals. Something like cultured meat, for example, twenty years ago was science fiction whereas now we’re seeing the first products,” David Pearce, philosopher and co-founder of the World Transhumanist Association, said.
Politically representing the growing movement in Britain, Mr. Pearce also claimed that since founding the movement back in 1998 with Nick Bostrom, it has managed to radically change along with the times, and in a good way as well.
“Back in 1998 the human genome hadn’t been decoded, most talk of super intelligence was of people taking smart drugs and radical life extension was still firmly in the realm of crank ally.
“Back in 1998 the human genome hadn’t been decoded, most talk of super intelligence was of people taking smart drugs and radical life extension was still firmly in the realm of crank ally.
The purely technical obstacles to transhumanism I’d say are diminishing. We are already seeing the first very controversial genome-edited babies in China,” he said. “Twenty years ago that would seem like utopian dreaming.”
However, Mr. Pearce also believes that to explore the possibilities that the movement offers, it will first have to overcome a high status quo bias.
However, Mr. Pearce also believes that to explore the possibilities that the movement offers, it will first have to overcome a high status quo bias.
“Even though it is now possible in principle to replace today’s genetic crack shot with designer babies there is tremendous status quo bias and most people will intend to continue having babies naturally,” he added.
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